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Analytical Sensitivity
A Phosphate-buffered saline (PBS) pool was spiked with drugs to target concentrations of ± 50% cut-off and ± 25% cut-off and tested with the Oral Fluid Drug Screen Device. The results are summarized below.
| Drug conc. (Cut-off range) |
n | COC | MAMP | PCP | |||
| - | + | - | + | - | + | ||
| 0% Cut-off | 30 | 30 | 0 | 30 | 0 | 30 | 0 |
| -50% Cut-off | 30 | 30 | 0 | 30 | 0 | 30 | 0 |
| -25% Cut-off | 30 | 30 | 0 | 28 | 2 | 30 | 0 |
| Cut-off | 30 | 20 | 10 | 23 | 7 | 22 | 8 |
| +25% Cut-off | 30 | 6 | 24 | 7 | 23 | 8 | 22 |
| +50% Cut-off | 30 | 0 | 30 | 0 | 30 | 0 | 30 |
| Drug conc. (Cut-off range) |
n | THC | OPI | AMP | |||
| - | + | - | + | - | + | ||
| 0% Cut-off | 30 | 30 | 0 | 30 | 0 | 30 | 0 |
| -50% Cut-off | 30 | 30 | 0 | 30 | 0 | 30 | 0 |
| -25% Cut-off | 30 | 24 | 6 | 26 | 4 | 26 | 4 |
| Cut-off | 30 | 15 | 15 | 20 | 10 | 19 | 11 |
| +25% Cut-off | 30 | 11 | 19 | 5 | 25 | 7 | 23 |
| +50% Cut-off | 30 | 0 | 30 | 0 | 30 | 0 | 30 |
The following tables lists the concentration of compounds (ng/mL) above which the Oral Fluid Drug Screen device for AMP/MAMP/COC/OPI/THC/PCP identified positive results at a read time of 10 minutes.
|
COCAINE |
ng/mL |
|
Benzoylecgonine |
20 |
|
Cocaine HCl |
20 |
|
Cocaethylene |
25 |
|
Ecgonine HCl |
1,500 |
| Ecgonine methyl ester | 12,500 |
|
AMPHETAMINE |
|
|
D-Amphetamine |
50 |
|
D,L-Amphetamine |
125 |
| b-Phenylethylamine |
4,000 |
| Tryptamine | 1,500 |
| p-Hydroxyamphetamine | 800 |
|
(±)3,4-Methylenedioxyamphetamine |
150 |
| L-Amphetamine |
4,000 |
|
METHAMPHETAMINE |
|
|
D-Methamphetamine |
50 |
| Fenfluramine | 60,000 |
|
p-Hydroxymethamphetamine |
400 |
| Methoxyphenamine | 25,000 |
|
(±)-3,4-Methylenedioxymethamphetamine |
50 |
|
L-Methamphetamine |
4,000 |
| Procaine | 2,000 |
| (1R,2S) - (-) Ephedrine | 400 |
|
MARIJUANA (THC) |
|
|
11-nor-A9 -THC-9 COOH |
12 |
| Cannabinol |
12,500 |
| 11-nor-A8-THC-9 COOH |
2 |
| A8 -THC |
6,000 |
| A9 -THC |
10,000 |
|
OPI |
|
|
Morphine |
40 |
|
Codeine |
10 |
|
Ethylmorphine |
24 |
|
Hydrocodone |
100 |
|
Hydromorphone |
100 |
|
Levophanol |
400 |
| Oxycodone | 25,000 |
|
6-Monoacetylmorphine |
25 |
|
Morphine 3-p-D-glucuronide |
50 |
|
Norcodeine |
1,500 |
|
Normorphone |
12,500 |
|
Oxycodone |
6,000 |
|
Oxymorphone |
25,000 |
| Diacetylmorphine (Heroin) |
50 |
|
Thebaine |
1,500 |
| Bilirubin | 3,500 |
|
PCP |
|
|
Phencyclidine |
10 |
| Tetrahydrozoline |
50,000 |
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