Drug Screen Test Card Sensitivity

Urine 1-Drug Card - AMPH (Amphetamine)

INNOVACON Labs single panel urine AMPH drug card is easy-to-use, very accurate, extremely inexpensive, and FDA-cleared testing for amphetamine drug use.

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Drug Screen Test Card Precision and Analytical Sensitivity

A study was conducted at three physician offices by untrained operators using three different lots of product to demonstrate the within run, between run and between operator precision. An identical panel of coded specimens, containing drugs at the concentration of ą 50% and ą 25% cut-off level, was labeled, blinded and tested at each site. The results are given below:

AMPHETAMINE (AMP)

Amphetamine conc. (ng/mL)	n per site	Site A		Site B		Site C
Amphetamine conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
500	15	15	0	15	0	14	1
750	15	13	2	11	4	11	4
1250	15	6	9	4	11	4	11
1500	15	2	13	1	14	1	14

BARBITURATES (BAR)

Secobarbital conc. (ng/mL)	n per site	Site A		Site B		Site C
Secobarbital conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
150	15	13	2	15	0	15	0
225	15	5	10	11	8	10	5
375	15	2	13	5	10	5	10
450	15	0	15	1	14	1	14

BENZODIAZEPINES (BZO)

Oxazepam conc. (ng/mL)	n per site	Site A		Site B		Site C
Oxazepam conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
150	15	14	1	14	1	15	0
225	15	11	4	14	1	14	1
375	15	0	15	1	14	3	12
450	15	0	15	0	15	0	15

COCAINE (COC)

Benzoylecgonine conc. (ng/mL)	n per site	Site A		Site B		Site C
Benzoylecgonine conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	14*	0	15	0	15	0
150	15	14	1	15	0	14	1
225	15	4	11	5	10	8	7
375	15	0	15	0	15	0	15
450	15	0	15	0	15	1	14

*Note: One invalid result was obtained.

COTININE (COT)

Cotinine conc. (ng/mL)	n per lot	Lot A		Lot B
Cotinine conc. (ng/mL)	n per lot	-	+	-	+
0	30	30	0	30	0
100	30	30	0	30	0
400	30	0	30	0	30

PROPOXYPHENE (PPX)

Propoxyphene conc. (ng/mL)	n per lot	Site A		Site B		Site C
Propoxyphene conc. (ng/mL)	n per lot	-	+	-	+	-	+
0	45	15	0	15	0	15	0
150	45	15	0	15	0	14	1
225	45	10	5	8	7	7	8
375	45	0	15	0	15	1	14
450	45	0	15	0	15	0	15

MARIJUANA (THC)

11-nor-09 -THC-9-COOH conc. (ng/mL)	n per site	Site A		Site B		Site C
11-nor-09 -THC-9-COOH conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
25	15	15	0	15	0	14	1
375	15	9	6	14	1	9	6
62.5	15	2	13	0	15	0	15
75	15	0	15	0	15	0	16

METHADONE (MTD)

Methadone conc. (ng/mL)	n per site	Site A		Site B		Site C
Methadone conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
150	15	12	3	15	0	15	0
225	15	5	7	14	1	15	0
375	15	0	15	0	15	1	14
450	15	1	14	0	15	0	15

METHAMPHETAMINE (mAMP)

Methamphetamine conc. (ng/mL)	n per site	Site A		Site B		Site C
Methamphetamine conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
500	15	15	0	14	1	13	2
750	15	21	4	10	5	10	5
1250	15	8	7	4	11	6	9
1500	15	1	14	1	14	0	15

Ecstasy (MDMA)

MDMA conc. (ng/mL)	n per site	Site A		Site B		Site C
MDMA conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
250	15	15	0	15	0	15	0
375	15	15	0	15	0	15	0
625	15	6	9	4	11	7	8
750	15	0	15	0	15	0	15

OPIATE 300 (MOP 300 OR OPI 300)

Morphine conc. (ng/mL)	n per site	Site A		Site B		Site C
Morphine conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
150	15	13	2	13	2	15	0
225	15	3	12	7	8	10	5
375	15	0	15	1	14	0	15
450	15	0	15	0	15	0	15

OPIATES (OPI 2000)

Morphine conc. (ng/mL)	n per site	Site A		Site B		Site C
Morphine conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
1000	15	15	0	15	0	14	1
1500	15	13	2	11	4	7	8
2500	15	4	11	1	14	2	13
3000	15	0	15	0	15	2	13

Oxycodone (OXY)

Oxycodone conc. (ng/mL)	n per site	Site A		Site B		Site C
Oxycodone conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
50	15	15	0	15	0	14	1
75	15	15	0	14	1	5	10
125	15	15	0	3	12	2	13
150	15	0	15	0	15	0	15

PHENCYCLIDINE (PCP)

Phencyclidine conc. (ng/mL)	n per site	Site A		Site B		Site C
Phencyclidine conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
12.5	15	15	0	14	1	14	1
18.75	15	11	4	13	2	10	5
31.25	15	8	7	5	10	1	14
37.5	15	4	11	0	15	0	15

TRICYCLIC ANTIDEPRESSANT (TCA)

Phencyclidine conc. (ng/mL)	n per site	Site A		Site B		Site C
Phencyclidine conc. (ng/mL)	n per site	-	+	-	+	-	+
0	15	15	0	15	0	15	0
500	15	15	0	14	1	14	1
750	15	11	4	13	2	10	5
1250	15	8	7	5	10	1	14
1500	15	4	11	0	15	0	15

Analytical Specificity

The following table lists the concentration of compounds (ng/mL) that are detected positive in urine by One Step Drug Screen Test Card at 5 minutes.

AMPHETAMINE	ng/mL
D-Amphetamine	1,000
D,L-Amphetamine sulfate	3,000
L-Amphetamine	50,000
(ą)3,4-Methylenedioxyamphetamine	2,000
Phentermine	3,000
BARBITURATES
Secobarbital	300
Amobarbital	300
Alphenol	150
Aprobarbital	200
Butabarbital	75
Butalbital	2,500
Butethal	100
Cyclopentobarbital	600
Pentobarbital	300
Phenobarbital	100
BENZODIAZEPINES
Oxazepam	300
Alprazolam	196
a-Hydroxyalprazolam	1,262
Bromazepam	1,562
Chlordiazepoxide	1,562
Chlordiazepoxide HCI	781
Clobazam	98
Clonazepam	781
Clorazepate dipotassium	195
Delorazepam	1,562
Desalkylflurazepam	390
Diazepam	195
Estazolam	2,500
Flunitrazepam	390
(ą) Lorazepam	1,562
RS-Lorazepam glucuronide	156
Midazolam	12,500
Nitrazepam	98
Norchlordiazepoxide	195
Nordiazepam	390
Oxazepam	300
Temazepam	98
Triazolam	2,500
COCAINE
Benzoylecgonine	300
Cocaine HCl	780
Cocaethylene	12,500
Ecgonine HCl	32,000
MARIJUANA (THC)
11-nor-A⁹ -THC-9 COOH	50
Cannabinol	20,000
11-nor-A⁸-THC-9 COOH	30
A8 -THC	15,000
A9 -THC	15,000

METHADONE
Methadone	300
Doxylamine	50,000
METHAMPHETAMINE
D-Methamphetamine	1,000
p-Hydroxymethamphetamine	30,000
L-Methamphetamine	8,000
(ą)-3,4-Methylenedioxymethamphetamine	2,000
Mephentermine	50,000
Ecstasy (MDMA)
D,L-3,4-Methylenedioxymethamphetamine (MDMA)	500
3,4-Methylenedioxyamphetamine	3,000
3,4-Methylenedioxyethyl-amphetamine (MDE)	300
OPIATE 300 (MOP)
Morphine	300
Codeine	300
Ethylmorphine	6,250
Hydrocodone	50,000
Hydromorphone	3,125
Levophanol	1500
6-Monoacetylmorphine	400
Morphine 3-p-D-glucuronide	1,000
Norcodeine	6,250
Normorphone	100,000
Oxycodone	30,000
Oxymorphone	100,000
Procaine	15,000
Thebaine	6,250
OPIATES (2000)
Morphine	2,000
Codeine	2,000
Ethylmorphine	5,000
Hydrocodone	12,500
Hydromorphone	5,000
Levophanol	75,000
6-Monoacetylmorphine	5,000
Morphine 3-p-D-glucuronide	2,000
Norcodeine	12,500
Normorphone	50,000
Oxycodone	25,000
Oxymorphone	25,000
Procaine	150,000
Thebaine	100,000
Oxycodone
Oxycodone	100
Codeine	50,000
Dihydrocodeine	12,500
Ethylmorphine	25,000
Hydrocodone	1,562
Hydromorphone	12,500
Oxymorphone	1,562
Thebaine	50,000
PCP
Phencyclidine	25
4-Hydroxyphencyclidine	12,500
TCA
Notriptyline	1,000
Nordoxepine	1,000
Trimipramine	3,000
Amitriptyline	1,500
Promazine	1,500
Desipramine	200
Imipramine	400
Clomipramine	12,500
Doxepine	2,000
Maprotiline	2,000
Promethazine	2,500

Effect of Urinary Specific Gravity

Fifteen (15) urine samples of normal, high, and low specific gravity ranges (1.000-1.037) were spiked with drugs at 50% below and 50% above cut-off levels respectively. The One Step Drug Screen Test Card was tested in duplicate using fifteen drug-free urine and spiked urine samples. The results demonstrate that varying ranges of urinary specific gravity does not affect the test results.

Effect of the Urinary pH

The pH of an aliquoted negative urine pool was adjusted to a pH range of 5 to 9 in 1 pH unit increments and spiked with drugs at 50% below and 50% above cut-off levels. The spiked, pH-adjusted urine was tested with One Step Drug Screen Test Card. The results demonstrate that varying ranges of pH does not interfere with the performance of the test.

Cross-Reactivity

A study was conducted to determine the cross-reactivity of the test with compounds in either drug-free urine or drug positive urine containing Cocaine, Barbiturates, Benzodiazepine, Amphetamine, Methamphetamine, Marijuana, Methadone, Opiate or Phencyclidine. The following compounds show no cross-reactivity when tested with One Step Drug Screen Test Card at a concentration of 100 pg/mL.

Product Home Page Features & Benefits Symptoms & Conditions
Instructions Performance Characteristics Compounds
Cross Reactivity Drug Detection Times FDA Clearance
Product Information Principle Sensitivity Treating Teens Book
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